منابع مشابه
Treatment for Hypoactive Sexual Desire
Flibanserin acts at cortical, limbic, hypothalamic, and brainstem nuclei to inhibit serotonin release by binding to 5-HT1A autoreceptors and block postsynaptic action of serotonin at 5-HT2A receptors. This gradually disinhibits the turnover of other monoamines like dopamine and noradrenaline that are critical for sexual desire.
متن کاملCircuits of sexual desire in hypoactive sexual desire disorder.
What Is HSDD? For both patients and health care providers, HSDD probably should mean “Having the Sexual Dysfunction Discussion” to diagnose and treat distressful conditions,1 but it really stands for Hypoactive Sexual Desire Disorder. The DSM-IV defines it as the persistent or recurring deficiency (or absence) of sexual fantasies or thoughts or desire for sexual activity associated with persona...
متن کاملTargeting circuits of sexual desire as a treatment strategy for hypoactive sexual desire disorder.
ISSUE Hypoactive sexual desire disorder (HSDD) is hypothesized to be a disorder of the brain's reward circuitry. Neurotransmitters in reward circuits are thus therapeutic targets for improving sexual desire. Novel treatment strategies are to enhance dopamine (DA) actions, reduce serotonin (5-HT) actions, or both.
متن کاملFlibanserin for Treating Hypoactive Sexual Desire Disorder
There have been several products developed for male sexual dysfunction. However, developing agents for female sexual dysfunction is lagging behind for various reasons. Sildenafil citrate (Viagra) and Tadalafil (Cialis), which have been prescribed for male sexual function disorders, are known to act on vessels.[1] On the other hand, flibanserin is thought to act on brain. Flibanserin has been ap...
متن کاملManagement of hypoactive sexual desire disorder.
Epidemiological studies have found that problems with sexual desire are one of the most common sexual complaints in females. Such complaints are far less common in males. In women, problems with sexual desire have been found to be associated with age, relationship duration, relationship distress, and complaints of anxiety and depression. Evidence-based interventions include cognitive behavioral...
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ژورنال
عنوان ژورنال: Cell
سال: 2015
ISSN: 0092-8674
DOI: 10.1016/j.cell.2015.10.015